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Heparin Protocol

Weight-based unfractionated heparin: initial bolus and maintenance infusion using standard 25 000 U / 50 cc syringe. Indication-specific dosing with hard maximum caps.

Bolus = U/kg × weight (capped) · Maintenance = U/kg/h × weight ÷ concentration (capped)
kg
U
cc
U/kg

Default 60 U/kg · max 4,000 U total.

U/kg/h

Default 12 U/kg/h · max 1,000 U/hr. Adjust against aPTT 1.5–2.5× control.

Check baseline aPTT, PT/INR, platelets, creatinine. Recheck aPTT 6 h after start and after every dose change.
Initial bolus
Units
Bolus volume to push
cc
Maintenance infusion
cc / hr
= units / hr & mass equivalent
Enter weight to compute bolus and infusion rate.

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